When Kyle's dreams are shattered by illness, he is at a loss as to what to do with his life. Everything he has worked for up until this moment has now been abruptly taken from him. He decides, in turn, to take his life rather than face the consequences of this tragedy. On the bus ride home, he encounters Amy, an eccentric individual with a different outlook on life. With the use of flashbacks and a few surprising twists, the audience discovers what has brought Kyle to his current conclusion and they learn that some things happen by choice and other's by coincidence. Life in Transit explores the idea of chance encounters, the 6 degrees of connection, and how one person can change the course of a stranger's life in a simple conversation.