Alice, a Professor of Comparative Religion, is writing a book exalting the ancient values of goddess mythologies and Feminine deity worship. One day she meets Jane, an enigmatic older woman who roams the university campus, sleeps under a bridge, and rattles Alice with her disturbing insights. At home, Alice is the muse to her partner Colette, an artist who is painting a series of goddess portraits. When Colette hears about Jane, she encourages a reluctant Alice to invite her over for dinner. "The Book of Jane" is a story of three women bound together by fate to advance the values of an ancient culture but at a deep cost no one expected.