马西娅·盖伊·哈登

Marcia Gay Harden

饰：Edda Mellas

海顿·潘妮蒂尔

Hayden Leslie Panettiere

饰：Amanda Knox

弗朗西斯科·德·维托

Francesco De Vito

饰：Ispettore Battistelli

Amanda Fernando Stevens

饰：Meredith Kercher

Djibril Kébé

Djibril Kébé

饰：Rudy Guede

Clive Walton

Clive Walton

饰：Curt Knox

Mimosa Campironi

Mimosa Campironi

饰：Filomena Romanelli

福斯托马里亚夏拉帕

Fausto Maria Sciarappa

饰：Detective Alicastro

杰·纳特尔

Jay Natelle

饰：Lloyd Halliday

Yasemin Sannino

饰：Lawyer Bongiorno

Matt Patresi

Matt Patresi

饰：Chris Mellas

Luciano Miele

饰：Dr. Ricardo Caparelli

Renato Cortesi

饰：Dr. Torre

Pilar Abella

Pilar Abella

饰：Daniela Borghese

David Callahan

David Callahan

饰：American TV Reporter,(as David Callahan)

安德森·库珀

Anderson Cooper

饰：Self,(archive footage)

Franco Trevisi

饰：Judge Micheli

Paolo Romio

饰：Raffaele Sollecito

Heather Cave

饰：Deanna Knox

提摩西·马丁

Timothy Martin

饰：Patrick Lumbana

肖布·卡浦尔

Shobu Kapoor

饰：Arlene Kercher,(as Shoboo Kapoor)

西莫内塔·索德

Simonetta Solder

饰：Detective Navarra

瓦伦蒂娜·卡尔内卢蒂

Valentina Carnelutti

饰：Dr. Patrizia Stefanoni

斯特凡诺·圣托斯帕戈

Stefano Santospago

饰：Lawyer Giordano

马帝亚·史巴吉亚

Mattia Sbragia

饰：Judge Massei

马修·T·雷诺德斯

Matthew T. Reynolds

饰：British Reporter,(as Matthew Reynolds)

罗伯托·诺毕雷

Roberto Nobile

饰：Dr. Luca Lalli

Marin Jo Finerty

Marin Jo Finerty

饰：Staci

Douglas Dean

饰：Carlo Rinaldi

Fabiana Formica

饰：Reporter #2

Daniele Monterosi

饰：Reporter #4

拉里·金

Larry King

饰：Self,(archive footage)