In a hospital, where pain sometimes turns into hope and where hope sometimes ends in crying, doctors, nurses and psychologists fight day by day to save the lives of their patients. However, they too undertake a fight of their own and face their own destinies. Guillermo, the director of the Hospital, after many years of being abandoned by his wife, rediscovers love in Oriana, a somewhat vulgar woman, but of great vitality. He will have to fight against the opposition of his daughter Martina and his mother Victoria. Martina, a neurosurgeon, will unexpectedly find love in a colleague, Fernando, who is married to Claudia and has many family problems. Martina and Fernando will live an intense romance, hidden and full of obstacles, but they will fight without respite to defend it. Rolo is a man who was a street boy. A man who has suffered a lot but who makes enormous efforts to improve himself. He works as a stretcher-bearer in the hospital and studies hard to receive a doctor's degree.