Mikkilineni was born in 1918 in Kolavennu, Krishna District, Andhra Pradesh, India as Radha Krishna Murthy Mikkilineni. He was an actor, known for Kula Gothralu (1962), Daana Veera Soora Karna (1977) and Seeta Kalyanam (1976). He was married to Seetaratnam. He died on February 23, 2011 in Vijayawada, Andhra Pradesh.